Autofluorescent structures in cultured WI-38 cells.
Published in Archives of Biochemistry and Biophysics
Microfabricated magnetic sifter for high-throughput and high-gradient magnetic separation.
Published in Journal of Magnetism and Magnetic Materials
A microfabricated magnetic sifter has been designed and fabricated for applications in biological sample preparation. The device enables high-throughput, high-gradient magnetic separation of magnetic nanoparticles by utilizing columnar fluid flow through a dense array (~5000/mm(2)) of micropatterned slots in a magnetically soft membrane. The potent...
Should post kidney transplantation hyperlipidemia considered a risk factor for graft function?
...Published in International journal of organ transplantation medicine
Ro/SSA and La/SSB specific IgA autoantibodies in serum of patients with Sjögren s syndrome and systemic lupus erythemato...
Published in Annals of the Rheumatic Diseases
Oxidative stress impairs the function of sarcoplasmic reticulum by oxidation of sulfhydryl groups in the Ca2+-ATPase.
Published in Archives of Biochemistry and Biophysics
Sarcoplasmic reticulum (SR) microsomes were oxidized by exposure to peroxydisulfate, hydrogen peroxide, or iron/ascorbate or by extended storage. The decline in Ca2+-ATPase activity, Ca2+ transport, and the increase in Ca2+ permeability which occurred under these conditions did not appear to result from lipid oxidation because these functional chan...
Permeability of membranes to amino acids and modified amino acids: mechanisms involved in translocation.
Published in Amino Acids
The amino acid permeability of membranes is of interest because they are one of the key solutes involved in cell function. Membrane permeability coefficients (P) for amino acid classes, including neutral, polar, hydrophobic, and charged species, have been measured and compared using a variety of techniques. Decreasing lipid chain length increased p...
Measurement of net proton-hydroxyl permeability of large unilamellar liposomes with the fluorescent pH probe, 9-aminoacr...
Published in Biochimica et Biophysica Acta
The fluorescent probe 9-aminoacridine was used to measure the rate of decay of experimentally established pH gradients across liposome membranes. From the rate of decay, separate permeability coefficients for protons (PH) and hydroxyls (POH) were calculated and summed to yield the net proton-hydroxyl permeability (Pnet). The net permeability of pro...
Influence of ionic inorganic solutes on self-assembly and polymerization processes related to early forms of life: impli...
Published in International Journal of Astrobiology
A commonly accepted view is that life began in a marine environment, which would imply the presence of inorganic ions such as Na+, Cl-, Mg2+, Ca2+, and Fe2+. We have investigated two processes relevant to the origin of life—membrane self-assembly and RNA polymerization—and established that both are adversely affected by ionic solute concentrations ...
National Profiles of Urinary Calculi: a Comparison Between Developing and Developed Worlds.
Published in Iranian journal of kidney diseases
Identification of influenza endonuclease inhibitors using a novel fluorescence polarization assay.
Published in ACS Chemical Biology
Influenza viruses have been responsible for the largest pandemics in the previous century. Although vaccination and prophylactic antiviral therapeutics are the primary defense against influenza virus, there is a pressing need to develop new antiviral agents to circumvent the limitations of current therapies. The endonuclease activity of the influen...
