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Pyrosequencing of the DNA gyrase gene in Neisseria species: effective indicator of ciprofloxacin resistance in Neisseria...

Lindbäck, E Unemo, M Akhras, M Gharizadeh, B Fredlund, H Nader Pourmand Wretlind, B

Published in Apmis

The quinolone resistance determining region (QRDR) of the gyrA gene in ciprofloxacin-susceptible strains (n=53) and strains of Neisseria spp. with reduced susceptibility (n=70) was determined by the pyrosequencing method. Results showed that the QRDR of the gyrA gene is an effective molecular indicator of resistance to ciprofloxacin in Neisseria go...

Molecular characterization of Neisseria gonorrhoeae identifies transmission and resistance of one ciprofloxacin-resistan...

Unemo, M Sjöstrand, A Akhras, M Gharizadeh, B Lindbäck, E Nader Pourmand Wretlind, B Fredlund, H

Published in Apmis

A highly discriminative and objective genetic characterization of N. gonorrhoeae, which increases our knowledge of strain populations in different geographic areas, is crucial for the development of improved control measures. In the present study, conventional phenotypic characterization and genetic characterization by means of pulsed-field gel ele...

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