Ro 52kD autoantibodies are detected in a subset of ANA-negative sera.
Published in Scandinavian Journal of Rheumatology
To define Ro 52kD, Ro 60kD, and La specificities of autoantibodies within ANA-negative sera, samples from 64 ANA-negative but SSA positive patients undergoing investigation due to suspected CTD were analysed, using recombinant antigens and synthetic peptides by immunoblotting and ELISA. The sera were selected from 4025 sera submitted for routine AN...